Cranial cruciate ligament disease is a complex, multifactorial disease characterized by disruption of the ligament, leading to stifle instability. Surgical procedures to alter joint mechanics are often costly, which can preclude some owners from pursuing this as a treatment option. A new veterinary device that is composed of collagen and elastin particles has been developed; it is delivered via intra-articular injection and helps protect cartilage from mechanical grinding. Previous anecdotal use of this product has suggested a possible benefit when used in dogs with cruciate injuries.
This pilot study seeks to evaluate whether this benefit is seen in a larger cohort of dogs with suspected cranial cruciate ligament rupture through the intra-articular injection of this product in the affected stifle joint. If a benefit is demonstrated, this data would support the launch of larger and more focused clinical studies to validate the use of this product in dogs for the pre-surgical management of cruciate disease.
Pet owners and veterinarians with eligible patients are invited to schedule a consultation with a participating surgeon at one of the Ethos hospitals near you.
- Dogs who are 6 months of age or older.
- Limping on the hindlimb that is suspected to be due to a partially or fully torn cranial cruciate ligament.
- There have been no previous surgical procedures on the affected joint 180 days prior to entering the study
- No -intra-articular injections within 90 days prior to entering the study
- No treatments with topical or systemic drugs that have analgesic (pain relieving) or anti-inflammatory properties within 3 days prior to the study (the study allows for rescue analgesics to be used if needed)
- No injectable corticosteroids or administration of polysulfated glycosaminoglycans, glucosamine, or chondroitin sulfate nutritional supplements within 30 days prior to enrollment
- No pregnant or lactating dogs
If you are a veterinarian and know of any clients with eligible patients who would be interested to learn more about the study, please ask them to consider scheduling a consultation appointment with the surgeon and hospital of their choice below.
- Bulger Veterinary Hospital, Lawrence, MA
- Massachusetts Veterinary Referral Hospital, Woburn, MA
- VSH-Sorrento Valley, San Diego, CA
- WVRC – Racine/Kenosha, Somers, WI
- WVRC – Waukesha, Waukesha, WI
Enroll or request more information below